Dr. John Dallon, Brigham Young University
Abstract: In this talk I will present two models for intermediate filament transport and analyze intermediate filament transport data. Intermediate filaments are one of three main fibrous structures of the cytoskeleton. How the cell controls the dynamic network made up of intermediate filaments is not understood. We developed two models of intermediate filament transport by motor molecules to help understand how the cell can regulate the network.One model is stochastic and considers individual motor molecules, whereas the other is an ODE formulation. By comparing results from the two models we can see how noise affects the system. Finally, we analyze fluorescence recovery after photobleaching (FRAP) data .
Bio: John Dallon graduated from the University of Utah with a Doctor of Philosophy in mathematics in 1996. He has worked at Brigham Young University since 1999. Before coming to BYU, Dr. Dallon was a research assistant at the University of Warwick and at Heriot-Watt University. While at BYU, Dr. Dallon has spent several months visiting: the Cell Polarity, Migration and Cancer Lab at the Institut Pasteur, Isaac Newton Institute for Mathematical Sciences, Politecnico di Torino, and the Division of Plastic Surgery, Department of Surgery at Penn State University College of Medicine. For more information see his website: https://math.byu.edu/~dallon/
Meeting ID: 998 2458 4542
Passcode: 475065