Interdisciplinary Center for Quantitative Modeling in Biology

MRB1

The 14th Annual Southern California Systems Biology Symposium (SoCal SysBio 2025)

Date: Saturday, May 10th, 2025
Location: Life Science 1500, UC Riverside
 

Join us for the 14th Annual Southern California Systems Biology Symposium (SoCal SysBio 2025), a premier event bringing together researchers from across Southern California to share cutting-edge research, foster community, and stimulate collaborations. This event will provide an opportunity for research groups from academic campuses and hospitals across Southern California to present their latest findings and promote collaborations in all areas of Systems and Computational Biology involving data-driven computational and machine learning modeling. This symposium will feature:

  • Invited Talks from leading experts in systems and computational biology
  • Lightning Talks for concise, impactful presentations based on posters
  • Poster Session showcasing the work of graduate students and postdoctoral researchers

Registration

  • The conference registration includes admission to the invited lectures, poster session and hosted lunch.
  • The deadline for Registration is April 30th, 2025. The total number of participants is limited and we would like to encourage early registration.
  • $25 per person - Please Register

Parking

Parking is free and will be available in LOT 6 Blue on Saturday, May 10th. Any overflow may opt to park in Lots 30 or 13 for free as well.

lifesciences1500 p6 map

>>Interactive Campus Map

List of Invited Speakers

Speaker Talk Title
Amjad Askary, Department of Molecular, Cell, & Developmental Biology, UCLA Identifying and Interpreting Patterns in the Cellular Architecture of Complex Tissues
Manuchehr Aminian, Mathematics & Statistics, Cal Poly Pomona Data-driven characterization of influenza-like illnesses and predicting time of exposure
Christina J. Edholm, Department of Mathematics, Scripps College Control Theory Applied for Infectious Diseases
David Frankhouser, Beckman Research Institute, City of Hope National Medical Center Longitudinal single cell RNA-sequencing reveals evolution of micro- and macro-states in chronic myeloid leukemia
Uduak George, Department of Mathematics & Statistics, SDSU

Sculpting Organs: The Role of Molecular and Biomechanical Cues in Morphogenesis
Alfonso Landeros, Statistics Department, UCR A modified tau-leaping method for gene regulatory networks
Carlos Lois, Biology, Caltech Reliability, variability and resilience of neuronal function
Yanping Ma; Mathematics, Statistics & Data Science; Loyola Marymount University Modeling the Disparate Impact of Epidemics on Disadvantaged Populations
Francesco Marangoni; Physiology & Biophysics, School of Medicine; UCI Synergy of biological and mathematical models to optimize checkpoint immunotherapy
Paul Newton, Aerospace & Mechanical Engineering, Mathematics & Quantitative & Computational Biology, USC Gaming the cancer-immunity cycle by synchronizing the dose schedules
Karen Paco, Henry E. Riggs School of Applied Life Sciences, Keck Graduate Institute Large Language Models Accurately Predict Antigen-Specific B Cell Receptors from Unselected Immune Repertoire Sequencing
Danielle Schmitt, Biochemistry, UCLA Illuminating Compartmentalized Regulation of Cellular Metabolism
Johannes Schoeneberg, Department of Pharmacology, UCSD 4D Cell Biology: Drug Discovery using Advanced Microscopy, Organoids, Digital Twins, and AI
Naveen Vaidya, Department of Mathematics and Statistics, SDSU Threshold Dynamics of Disease Transmission via Math-model Informed Neural Networks (MINN)
Shahab Vahdat, Bioengineering Department, UCR Simultaneous Imaging of Brain and Spinal Cord Circuits in humans
Yixian Wang, Department of Chemistry & Biochemistry, CSULA Nanoscale Imaging of α-Synuclein-Induced Membrane Disruption in SH-SY5Y Neuroblastoma Cells Using Scanning Ion Conductance Microscopy
Max Wilson; Molecular, Cellular & Developmental Biology; UCSB Optogenetic Engineering of Cell Behaviors for Discovery and Therapy
Katherine Xue, Departments of Molecular Biology & Biochemistry & Ecology & Evolution, UCI Ecology of colonization in the human gut microbiome

Schedule

8:00 a.m. Check-in & Refreshments
8:45 a.m.

Welcome & Introduction
9:00 a.m.

Manuchehr Aminian (Cal Poly Pomona)

 Data-driven characterization of influenza-like illnesses and predicting time of exposure
9:20 a.m. Amjad Askary (UCLA) Identifying and Interpreting Patterns in the Cellular Architecture of Complex Tissues
9:40 a.m. Shahab Vahdat (UCR) Simultaneous Imaging of Brain and Spinal Cord Circuits in humans
10:00 a.m.

David Frankhouser (City of Hope National Medical Center)

 Longitudinal single cell RNA-sequencing reveals evolution of micro- and macro-states in chronic myeloid leukemia
10:20 a.m. Alfonso Landeros (UCR) A modified tau-leaping method for gene regulatory networks
10:40 - 11:10 a.m. Coffee Break
11:10 a.m. Uduak George (SDSU) Sculpting Organs: The Role of Molecular and Biomechanical Cues in Morphogenesis
11:30 a.m. Carlos Lois (Caltech) Reliability, variability and resilience of neuronal function
11:50 a.m. Yanping Ma (LMU) Modeling the Disparate Impact of Epidemics on Disadvantaged Populations
12:10 p.m. Lightning Talks
12:50 - 2:10 p.m. Lunch & Poster Session
2:10 p.m. Francesco Marangoni (UCI) Synergy of biological and mathematical models to optimize checkpoint immunotherapy
2:30 p.m. Paul Newton (USC) Gaming the cancer-immunity cycle by synchronizing the dose schedules
2:50 p.m. Karen Paco, (KGI) Large Language Models Accurately Predict Antigen-Specific B Cell Receptors from Unselected Immune Repertoire Sequencing
3:10 p.m. Danielle Schmitt (UCLA) Illuminating Compartmentalized Regulation of Cellular Metabolism
3:10 - 3:50 p.m. Coffee Break
3:50 p.m. Johannes Schoeneberg (UCSD) 4D Cell Biology: Drug Discovery using Advanced Microscopy, Organoids, Digital Twins, and AI
4:10 p.m. Christina J. Edholm (Scripps College) Control Theory Applied for Infectious Diseases
4:30 p.m. Naveen Vaidya (SDSU) Threshold Dynamics of Disease Transmission via Math-model Informed Neural Networks (MINN)
4:50 p.m. Max Wilson (UCSB) Optogenetic Engineering of Cell Behaviors for Discovery and Therapy
5:10 p.m. Yixian Wang (CSULA) Nanoscale Imaging of α-Synuclein-Induced Membrane Disruption in SH-SY5Y Neuroblastoma Cells Using Scanning Ion Conductance Microscopy
5:30 p.m. Katherine Xue (UCI) Ecology of colonization in the human gut microbiome

Organizing Committee

Sponsors